Test and Clinical Application

SEBIA Capillary electrophoresis (CE) is the next generation separation method that provides clear-cut and precise separation of the HbA1c fraction with no altered results in the presence of the most frequent interferences (labile A1c, carbamylated Hb, HbF, heterozygous S, C, D and E). The high resolution power of the method allows the incidental detection of […]

SEBIA Capillary electrophoresis (CE) is the next generation separation method that provides clear-cut and precise separation of the HbA1c fraction with no altered results in the presence of the most frequent interferences (labile A1c, carbamylated Hb, HbF, heterozygous S, C, D and E). The high resolution power of the method allows the incidental detection of homozygous hemoglobin variants (sickle cell disease) preventing the laboratories to report HbA1c incorrectly in the absence of HbA.

The SEBIA HbA1c by CE is done by using the exact same calculation formula as the one used by the IFCC reference method for the worldwide assay standardization: HbA1c/(HbA1c+HbA0), thus ensuring reliable results in all circumstances.